A Case of Infliximab-induced Multifocal Motor Neuropathy in a Patient with Rheumatoid Arthritis and Literature Review
نویسندگان
چکیده
Tumor necrosis factor (TNF) inhibitors are increasingly used in treatment of rheumatoid arthritis (RA), ankylosing spondylitis, psoriatic arthritis, and inflammatory bowel diseases including Crohn’s disease and ulcerative colitis. Rarely, anti-TNF therapy is associated with neurological complications, including both central and peripheral nervous system disorders. To the best of our knowledge, only one case of infliximab-associated multifocal motor neuropathy with conduction block in a patient with spondyloarthropathy has been reported to date in Korea. Here, we report on the case of a 58-year-old Korean woman affected by RA who developed multifocal motor neuropathy after infliximab treatment. (J Rheum Dis 2016;23:250-255)
منابع مشابه
Bilateral Synovial Knee Chondromatosis in a Patient with Rheumatoid Arthritis: Case-report and Literature Review
We presented a female patient with RA complaining of progressive pain, swelling, and crepitation of the knee joints that was diagnosed with bilateral synovial chondromatosis (SC) of both knees. Radiographies revealed characteristic findings of SC including multiple calcified multifaceted loose bodies within both knees. Removal of cartilaginous segments as well as total synovectomy was performed...
متن کاملSimultaneous Quadruple Joint Replacement (QJR) in Disabling Juvenile Rheumatoid Arthritis – a Case Report with Review of Literature
We wish to present a case of 47-year-old patient with Juvenile Rheumatoid Arthritis and ankylosis of both hips and bothknees treated by bilateral hip and knee arthroplasty in a single anaesthesia i.e. Quadruple joint replacement in singlesitting. He was back on his feet from his bed-ridden state within the fortnight following surgery. He has been followedup for four years and has been performin...
متن کاملSulfasalazine plus Chloroquine-Induced Mood Disorder in a Patient with Rheumatoid Arthritis
Rheumatoid arthritis is a chronic systemic inflammatory disease that affects approximately 0.5-1% of the world population. The current approach to this disease is to start an intensive treatment without delay once the disease has developed. Various studies in the literature have shown that combination of disease modifying antirheumatic drugs such as sulfasalazine and chloroquine offers a more a...
متن کاملA case of multifocal-motor-neuropathy-like disease with conduction blocks under infliximab with spontaneous progressive recovery.
Treatments with anti-TNF alpha (ATA) are now commonly used in certain inflammatory rheumatic diseases such as spondyloarthritis, rheumatoid arthritis or psoriatic arthritis, and inflammatory bowel disease (IBD). Among the different therapeutic classes available, there are, firstly, chimeric or humanized monoclonal antibody such as infliximab (Remicade) and adalimumab (Humira) and, secondly, eta...
متن کاملPeripheral neuropathy during infliximab therapy for rheumatoid arthritis.
Infliximab is a tumor necrosis factor (TNF) alpha antagonist used successfully in the treatment of rheumatoid and seronegative arthritis, Crohn’s disease, psoriasis, and severe cases of vasculitis. Main side effects of this drug are: hypersensitivity syndrome, infections, drug-induced lupus, retrobulbar optic neuritis. Central demyelinating diseases associated with TNFalpha antagonist have been...
متن کامل